Tetrahydrocannabinol (THC), which is the primary psychoactive compound in cannabis, has been studied for its potential effects on sleep. While there is some evidence suggesting that THC may help with sleep, it's important to note that research in this area is still ongoing, and the results can vary.
Several studies have explored the effects of THC on sleep in humans. One study published in the journal Sleep found that THC administration decreased the time it took for participants to fall asleep and increased the amount of time spent in deep sleep. However, it also increased the occurrence of sleep disruptions and reduced the amount of REM sleep, which is associated with dreaming. Another study published in the Journal of Clinical Psychopharmacology investigated the effects of synthetic THC on sleep. The researchers observed that THC reduced the time it took to fall asleep, increased overall sleep duration, and decreased the number of awakenings during the night. However, it also caused residual drowsiness and impaired cognitive performance the next day. While these studies suggest that THC may have some sleep-promoting effects, it's worth noting that the results are not consistent across all individuals. Additionally, THC's influence on sleep can be influenced by factors such as dosage, timing, and an individual's tolerance to cannabis. The effects can also be influenced by the presence of other compounds found in cannabis, such as cannabidiol (CBD), which has been suggested to have more calming and sedating properties
Cannabidiol (CBD), a non-psychoactive compound found in cannabis, has also been studied for its potential effects on sleep. While the research on CBD and sleep is still relatively limited, there is some evidence suggesting that it may have sleep-promoting properties. Several studies have explored the effects of CBD on sleep in humans.
A study published in the journal Current Psychiatry Reports reviewed the existing literature and found that CBD may have potential therapeutic benefits for sleep disorders. It indicated that CBD may help with sleep by reducing anxiety, which is a common contributor to insomnia and sleep disturbances. Another study published in the Permanente Journal investigated the effects of CBD on sleep and anxiety in a clinical population. The researchers observed that anxiety scores decreased in the first month for most patients, and sleep scores improved in the first month for around two-thirds of the patients. However, it's important to note that this study was conducted with a relatively small sample size. Additionally, a review published in the journal Medicines concluded that CBD shows promise in improving sleep in individuals with conditions such as chronic pain, Parkinson's disease, and post-traumatic stress disorder (PTSD). The review highlighted CBD's potential to address the underlying causes of sleep disturbances and promote better sleep quality.
Cannabinol (CBN) is a minor cannabinoid found in cannabis plants. It is typically present in low concentrations and is produced through the degradation of tetrahydrocannabinol (THC). THC is the primary psychoactive compound in cannabis, while CBN is not known for its psychoactive effects.
CBN has been suggested to have sedative properties and potentially promote sleep.
Some studies conducted on animals have shown that CBN may have sleep-enhancing effects, but it's important to note that animal research does not always directly translate to human effects.
Regarding human research, there are limited clinical studies specifically investigating CBN's effects on sleep. An older study published in 1975 tested the effects of CBN on sleep in six male participants and reported mild sedative properties but noted that the effects were not as potent as other sleep-inducing medications.